A normal alveolar dead space fraction plus D-dimer assay ruled out suspected pulmonary embolism in the emergency department
نویسندگان
چکیده
منابع مشابه
Normal D-dimer levels in emergency department patients suspected of acute pulmonary embolism.
OBJECTIVES We sought to determine:1) whether normal D-dimer enzyme-linked immunosorbent assay (ELISA) assays predicted the absence of pulmonary embolism (PE) in the high-volume emergency department (ED) of the Brigham and Women's Hospital, and 2) whether ED physicians accepted normal D-dimer levels as confirmation of no PE without further diagnostic testing such as lung scanning, chest computed...
متن کاملA higher d-dimer threshold safely rules-out pulmonary embolism in very elderly emergency department patients.
INTRODUCTION D-dimer is commonly used in the workup of suspected Pulmonary Embolism (PE), but its specificity decreases with age. We evaluated whether using a higher cutoff value for D-dimer could increase the test specificity without reducing its sensitivity for ruling-out PE in elderly and very elderly patients presenting to the Emergency Department (ED). MATERIAL AND METHODS All patients w...
متن کاملSteady-state end-tidal alveolar dead space fraction and D-dimer: bedside tests to exclude pulmonary embolism.
STUDY OBJECTIVE Less than 35% of patients suspected of having pulmonary embolism (PE) actually have PE. Safe bedside methods to exclude PE could save health-care resources and improve access to diagnostic testing for suspected PE. In patients with suspected PE, we sought to determine the sensitivity, specificity, and negative predictive value of (1) a steady-state end-tidal alveolar dead space ...
متن کاملD-dimer for Suspected Pulmonary Embolism
1 Leung RS, Bradley DT. Sleep apnea and cardiovascular disease. Am J Respir Crit Care Med 2001; 164:2147– 2165 2 Shahar E, Whitney CW, Redline S, et al. Sleep-disordered breathing and cardiovascular diseases: cross sectional results of the Sleep Heart Health Study. Am J Respir Crit Care Med 2001; 163:19–25 3 Nieto FJ, Young TB, Lind BK, et al. Association of sleepdisordered breathing, sleep apn...
متن کاملMethodology for a rapid protocol to rule out pulmonary embolism in the emergency department.
We propose an emergency department (ED) pulmonary embolism rule-out protocol based on pretest probability assessment coupled with either a negative D -dimer assay result or a negative D -dimer assay result plus a normal alveolar dead-space measurement. We examine the safety, efficiency, and feasibility of such a protocol, paying special attention to implicit and explicit strategies of pretest p...
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ژورنال
عنوان ژورنال: Evidence-Based Medicine
سال: 2001
ISSN: 1356-5524
DOI: 10.1136/ebm.6.5.158